[HTML][HTML] Comparative study of different crystallization methods in the case of cilostazol crystal habit optimization

T Tari, P Szabó-Révész, Z Aigner - Crystals, 2019 - mdpi.com
cilostazol is limited owing to its poor aqueous solubility and oral bioavailability. Our aim was
to produce cilostazol … size distribution and stable polymorphic form to increase its dissolution …

[PDF][PDF] Hydrophilic sugars for enhancing dissolution rate of cilostazol: effect of wet co-processing

AY Bazeed, A Nouh, EA Essa… - Pharmaceutical …, 2020 - ps.tbzmed.ac.ir
… cooling of cilostazol is believed to result in polymorphic transition… It may possibly reflect
polymorphic transition of the drug in … Polymorphism has been reported for cilostazol upon thermal …

Preparation and optimization of glyceryl behenate-based highly porous pellets containing cilostazol

KM Hwang, W Byun, CH Cho… - Pharmaceutical …, 2018 - Taylor & Francis
… reported cases of cilostazol polymorphism after melting and coolingCitation 40 , the sintering
temperature used in this study was not high enough to alter its crystalline form. The FTIR …

[HTML][HTML] An oral formulation of cilostazol nanoparticles enhances intestinal drug absorption in rats

C Yoshioka, Y Ito, N Nagai - Experimental and …, 2018 - spandidos-publications.com
… Therefore, we are now investigating the effect of each of the CLZ polymorphic forms (Form
AC) in the CLZ/Rnano tablet on stability in re-dispersion, drug absorption, and treatment of …

[HTML][HTML] Cilostazol-loaded poly (ε-Caprolactone) electrospun drug delivery system for cardiovascular applications

M Rychter, A Baranowska-Korczyc, B Milanowski… - Pharmaceutical …, 2018 - Springer
… B, which may spontaneously convert overtime back to form A … incorporation of the hydrophobic
drug - cilostazol (CIL) into the … Our study demonstrates no change in CIL polymorphic form

Crystal habit optimization by means of impinging jet crystallization method

T Tari - 2019 - search.proquest.com
polymorph, Forms B and C are metastable, and Form C has a monoclinic crystal structure
[93]. Cilostazol … bioavailability, the therapeutic usage of cilostazol is limited. Therefore, several …

[PDF][PDF] Department of pharmaceutics, faculty of pharmacy, university of Kufa, Al-Najaf, Iraq. 2 Department of pharmaceutics, Collage of pharmacy, Mustansiriyah …

AN Wannas, NK Maraie, MHM Ali… - Journal of Natural …, 2021 - alrasheedcol.edu.iq
… maintained>90% of cilostazol in the solubilized form after 3 hours in non- … to prepare cilostazol
liquid oral dosage form using … Thermallyprepared polymorphic forms of cilostazol. J Pharm …

[HTML][HTML] A systematic approach to the development of cilostazol nanosuspension by liquid antisolvent precipitation (LASP) and its combination with ultrasound

E Jakubowska, B Milanowski, J Lulek - International Journal of Molecular …, 2021 - mdpi.com
… has been able to generate any polymorphic form other than A for cilostazol, unlike for many
… govern the resulting crystalline form [81]. The chemical identity of cilostazol in every sample …

Electrospun poly (lactic acid)(PLA)/poly (butylene adipate-co-terephthalate)(PBAT) nanofibers for the controlled release of cilostazol

LR Antunes, GL Breitenbach, MCG Pellá… - International Journal of …, 2021 - Elsevier
… Pure cilostazol presented peaks at 2θ angles of about 9.2, 12.8, 15.5, 18.6, 19.3, and 31.4
[… of form A of cilostazol [45]. However, the mixture of the three polymorphic forms [41,46] in the …

Molecular dynamics simulation, thermodynamic parameters and solute–solvent molecular interactions of cilostazol (form A) dissolution in (ethylene glycol/ethanol+ …

G Xia, Z Luo, Y Yang, L Chen, R Li, C Du… - The Journal of Chemical …, 2024 - Elsevier
… adopted to analyze the crystalline form of the raw materials and equilibrium solid phase
after experiments in each systems. The equilibrated cilostazol was recovered from equilibrium …